学科 : 生物医学工程
方向 :聚焦超声医学应用：经颅神经调控，血栓消融，肿瘤消融。多模态生理信号采集，医学影像处理
电子邮件 :suo@bit.edu.cn
办公地址 :7号教学楼407
个人简历
索鼎杰，北京理工大学特别副研究员、硕士生导师。研究方向为超声医学、神经调控、脑机接口和医学影像。致力于聚焦超声的医学应用，包括急性脑血栓消融、肿瘤消融和神经调控，在聚焦超声参数优化、微泡声空化动力学仿真、个体化经颅超声导航和大脑功能连接等方面均有研究。相关工作共发表 SCI 论文 20余 篇，第一作者/通讯作者 7 篇，其中有4篇 Q1 区 Top 论文分别发表在 Ceberal Cortex、Applied physics letters、Ultrasonics sonochemistry和IEEE Transactions on Neural Systems And Rehabilitation Engineering 上（一篇被杂志编辑评为“editor's pick”），另外两篇 Q2 分别发表在 Physicsin medicine and biology 和 Journal of applied physics 上。此外多篇参与论文也属 Q1 区分别发表在 Radiology，Nano research 上，总引用数 500+。
教育培训经历
2014-01至2017-10，博士，机械工程，北卡罗来纳州立大学，北卡
2012-08至2013-12，硕士，机械工程，南加州大学，加州
2011-07至2012-06，本科，机械工程，北卡罗来纳州立大学，北卡
2008-09至2011-06，本科，机械工程及自动化，北京理工大学，北京
工作经历
2020-09 至今，北京理工大学, 生命学院, 副研究员
2020-01 至 2020-08 美国，Shockwave Medical Inc.，研究与开发部(Research and Development)，高级工程师
2017-12 至 2019-12，美国，华盛顿大学，博士后
学术任职
《Applied Physics Letters》、《Ultrasonics Sonochemistry》、《Ultrasonics》、《Journal of Applied Physics》、 《Ultrasonic Imaging》、《Frontiers in Acoustics》、《Frontiers in Neurorobotics》、《Frontiers in Neuroscience》、《Chemical Engineering Research and Design》、《Experimental Thermal and Fluid Science》、《Current Pharmaceutical Biotechnology》和《Journal of Industrial Textiles》审稿人；
中国声学学会，中国生理学会，中国生物医学工程学会，北京生理科学会，The Acoustical Society of America, IEEE等会员
研究领域
主要研究方向：超声医学应用：神经调控，溶栓，肿瘤消融。
讲授课程
《医学影像技术》《现代医疗仪器与设备》《人工智能与脑科学》《专业实习》
教材及专著
参与项目
· 国家自然科学基金委员会，青年项目，12104049，基于声空化理论的双频聚焦超声激励微泡开放血脑屏障机制研究，2022年01月至2024年12月，30万元，在研，主持；
· 北京理工大学，青年教师学术启动计划，XSQD-202010004，低强度超声脑刺激，2021年01月至2023年12月, 40万元，在研，主持；
· 科塞尔医疗科技(苏州)有限公司，横向课题，超声声场扫描系统技术开发合同，2022年10月至2024年04月，50万元，在研，主持；
· 北京和成系统科技有限责任公司，横向课题，球囊型冲击波系统声学技术服务，2022年03月至2023年03月，20万元，在研，主持；
· 北京理工大学，仪器设备自制（改制），基于 LabVIEW 的三轴声场扫描系统软件开发，2022年01月至2022年12月，1.5万元，已结题，主持；
· 中国生物技术发展中心，科技创新重大项目，2022ZD0206508，新型无创BCI理论模型与平台，2022年8月至2027年7月，197.4万，在研，参与；
· 北京市科学技术委员会，重大专项，Z201100007720009，基于精准电刺激调控技术的脑功能增强研究，2020年06月至2022年05月，320万，已结题，参与；
· 美国国防部，癌症创新研究专项，超声介入药物释放在实验猪上的研究，A118007，2017年09月至2019年09月，50万美元（350万），已结题，参与；
· 美国国立卫生研究院，R01，经颅聚焦超声溶栓研究，2014年01月至2017年12月，30万美元（210万），已结题，参与；
SCI Journal paper
1. T. Yan, G. Wang, T. Liu, G. Li, C. Wang, S. Funahashi, Dingjie Suo*, and G. Pei, “Effects of Microstate Dynamic Brain Network Disruption in Different Stages of Schizophrenia,” IEEE Trans Neural Syst Rehabil Eng, vol. 31, pp. 2688-2697, 2023.
2. T. Yan, G. Wang, L. Wang, T. Liu, T. Li, L. Wang, D. Chen, S. Funahashi, J. Wu, B. Wang, and Dingjie Suo*, “Episodic memory in aspects of brain information transfer by resting-state network topology,” Cereb Cortex, vol. 32, no. 22, pp. 4969-4985, 2022.
3. Y. Yang, Z. Chen, J. Zhang, G. Wang, R. Zhang, and Dingjie Suo*, “Preparation and Applications of the Cellulose Nanocrystal,” International Journal of Polymer Science, vol. 2019, pp. 1767028, 2019.
4. Dingjie Suo*, Bala Govind, Juanjuan Gu, Paul A. Dayton, Yun Jing. “Dynamic assessment of dual-frequency microbubble-mediated sonothrombolysis in vitro.” J. Appl. Phys., 125(8), 2019.
5. Dingjie Suo*, Bala Govind, Shengqi Zhang, Yun Jing. “Numerical investigation of inertial cavitation threshold under multi-frequency ultrasound.” Ultrasonics sonochemistry, 2017.
6. Dingjie Suo*, Zhiyang Jin, Xiaoning Jiang, Paul Dayton, and Yun Jing. "Microbubble mediated dual-frequency high intensity focused ultrasound thrombolysis: an in vitro study." Applied physics letters, 2016.
7. Dingjie Suo*, Sijia Guo, Weili Lin, Xiaoning Jiang, and Yun Jing. "Thrombolysis using multi-frequency high intensity focused ultrasound at MHz range: an in vitro study." Physics in medicine and biology, 2015.
8. Z. Han, T. Liu, Z. Shi, J. Zhang, Dingjie Suo*, L. Wang, D. Chen, J. Wu, and T. Yan, “Investigating the heterogeneity within the somatosensory-motor network and its relationship with the attention and default systems,” PNAS Nexus, vol. 2, no. 9, pp. pgad276, 2023.
9. J. Zhang, Y. Yang, T. Liu, Z. Shi, G. Pei, L. Wang, J. Wu, S. Funahashi, Dingjie Suo*, C. Wang, and T. Yan, “Functional connectivity in people at clinical and familial high risk for schizophrenia,” Psychiatry Res, vol. 328, pp. 115464, 2023.
10. Z. Shi, L. Ding, X. Han, B. Jiang, J. Zhang, Dingjie Suo*, J. Wu, G. Pei, B. Fang, and T. Yan, “Multimodal biofeedback for Parkinson’s disease motor and nonmotor symptoms,” Brain Science Advances, vol. 9, no. 2, pp. 136-154, 2023.
11. Z. Shi, B. Jiang, T. Liu, L. Wang, G. Pei, Dingjie Suo*, J. Zhang, S. Funahashi, J. Wu, and T. Yan, “Individual-level functional connectomes predict the motor symptoms of Parkinson’s disease,” Cerebral Cortex, vol. 33, no. 10, pp. 6282-6290, 2023.
12. T. Li, L. Wang, Z. Piao, K. Chen, X. Yu, Q. Wen, Dingjie Suo*, C. Zhang, S. Funahashi, G. Pei, B. Fang, and T. Yan, “Altered Neurovascular Coupling for Multidisciplinary Intensive Rehabilitation in Parkinson's Disease,” J Neurosci, vol. 43, no. 7, pp. 1256-1266, 2023.
13. Z. Shi, B. Jiang, S. Liang, J. Zhang, Dingjie Suo*, J. Wu, D. Chen, G. Pei, and T. Yan, “Claw-shaped flexible and low-impedance conductive polymer electrodes for EEG recordings: Anemone dry electrode,” Science China Technological Sciences, vol. 66, no. 1, pp. 255-266, 2023.
14. S. Liu, D. Zhang, Z. Liu, M. Liu, Z. Ming, T. Liu, Dingjie Suo*, S. Funahashi, and T. Yan, “Review of brain–computer interface based on steady‐state visual evoked potential,” Brain Science Advances, vol. 8, no. 4, pp. 258-275, 2022.
15. D. Zhang, S. Liu, J. Zhang, G. Li, Dingjie Suo*, T. Liu, J. Luo, Z. Ming, J. Wu, and T. Yan, “Brain-Controlled 2D Navigation Robot Based on a Spatial Gradient Controller and Predictive Environmental Coordinator,” IEEE Journal of Biomedical and Health Informatics, vol. 26, no. 12, pp. 6138-6149, 2022.
16. G. Pei, X. Liu, Q. Huang, Z. Shi, L. Wang, Dingjie Suo*, S. Funahashi, J. Wu, J. Zhang, and B. Fang, “Characterizing cortical responses to short-term multidisciplinary intensive rehabilitation treatment in patients with Parkinson's disease: A transcranial magnetic stimulation and electroencephalography study,” Front Aging Neurosci, vol. 14, pp. 1045073, 2022.
17. J. Wu, C. Wang, L. Wang, Y. Wang, J. Yang, T. Yan, Dingjie Suo*, L. Wang, X. Liu, and J. Zhang, “Development of a Piezoelectric Actuated Tactile Stimulation Device for Population Receptive Field Mapping in Human Somatosensory Cortex With fMRI,” J Magn Reson Imaging, vol. 56, no. 4, pp. 1055-1065, 2022.
18. T. Liu, L. Wang, Dingjie Suo*, J. Zhang, K. Wang, J. Wang, D. Chen, and T. Yan, “Resting-State Functional MRI of Healthy Adults: Temporal Dynamic Brain Coactivation Patterns,” Radiology, vol. 304, no. 3, pp. 624-632, 2022.
19. J. Wang, K. Wang, T. Liu, L. Wang, Dingjie Suo*, Y. Xie, S. Funahashi, J. Wu, and G. Pei, “Abnormal Dynamic Functional Networks in Subjective Cognitive Decline and Alzheimer's Disease,” Front Comput Neurosci, vol. 16, pp. 885126, 2022.
20. J. Zhang, T. Liu, Z. Shi, S. Tan, Dingjie Suo*, C. Dai, L. Wang, J. Wu, S. Funahashi, and M. Liu, “Impaired Self-Referential Cognitive Processing in Bipolar Disorder: A Functional Connectivity Analysis,” Front Aging Neurosci, vol. 14, pp. 754600, 2022.
21. A. Clark, S. Bonilla, Dingjie Suo*, Y. Shapira, and M. Averkiou, “Microbubble-Enhanced Heating: Exploring the Effect of Microbubble Concentration and Pressure Amplitude on High-Intensity Focused Ultrasound Treatments,” Ultrasound Med Biol, vol. 47, no. 8, pp. 2296-2309, 2021.
22. S. B. Keller, Dingjie Suo*, Y. N. Wang, H. Kenerson, R. S. Yeung, and M. A. Averkiou, “Image-Guided Treatment of Primary Liver Cancer in Mice Leads to Vascular Disruption and Increased Drug Penetration,” Front Pharmacol, vol. 11, pp. 584344, 2020.
23. Di, Jin, Jicheng Yu, Qun Wang, Shanshan Yao, Dingjie Suo*, Yanqi Ye, Matthew Pless, Yong Zhu, Yun Jing and Zhen Gu. "Ultrasound-triggered noninvasive regulation of blood glucose levels using microgels integrated with insulin nanocapsules." Nano research. 2017.
24. Y. Xie, C. Shen, W. Wang, J. Li, Dingjie Suo*, B.-I. Popa, Y. Jing, and S. A. Cummer, “Acoustic Holographic Rendering with Two-dimensional Metamaterial-based Passive Phased Array,” Scientific Reports, vol. 6, no. 1, pp. 35437, 2016.
EI Journal paper
1. X. Huang, Z. Ji, X. Liu, T. Yan, J. Wu, and D. Suo, "Dynamic simulation and optimization of the inertial cavitation threshold under dual-frequency ultrasound." 2022 16th ICME International Conference on Complex Medical Engineering (CME)
2. B. Gao, Dingjie Suo*, T. Yan, J. Zhang, J. Zhang, S. Funahashi, and J. Wu, "EEG Microstate Analysis of Transcranial Alternating Current Stimulation in Healthy People." 2022 16th ICME International Conference on Complex Medical Engineering (CME),pp. 165-168.
3. S. Wang, J. Wu, D. Zhang, Dingjie Suo*, and T. Yan, "An Algorithm for Motor Imagery Classification Based on Transfer Learning and Feature Fusion." 2022 16th ICME International Conference on Complex Medical Engineering (CME),pp. 246-251.
4 J. Zhang, Z. Yan, J. Zhang, X. Wang, A. Kang, B. Gao, Dingjie Suo*, T. Yan, and J. Wu, "Application of Triangular Waveform for Transcranial Alternating Current Stimulation in Working Memory." 2022 16th ICME International Conference on Complex Medical Engineering (CME),pp. 318-322.
5. Z. Yan, J. Zhang, J. Zhang, J. Wu, A. Kang, Dingjie Suo*, T. Yan, and J. Wang, "The Comparative Analysis of Different HD-TES Montages." 2022 16th ICME International Conference on Complex Medical Engineering (CME),pp. 232-235.
6. Z. Shi, X. Han, B. Jiang, J. Zhang, Dingjie Suo*, G. Pei, T. Yan, Y. Wang, J. Wu, and J. Wang, "Wearable Multimodule Bio-signal Acquisition System: Brain Multi-Plus." 2022 16th ICME International Conference on Complex Medical Engineering (CME),pp. 77-80.
7. J. Zhang, J. Zhang, Z. Shi, Dingjie Suo*, T. Yan, Z. Zhang, and J. Wu, "Development of an Electrical Stimulator System for Tactile Temporal and Spatial Study." 2022 16th ICME International Conference on Complex Medical Engineering (CME),pp. 290-293.
中文论文
专利
[1]闫天翼,张鑫鑫,索鼎杰*等. 一种触觉感知的动态闭环脑功能拓扑图测量与分型系统[P]. 北京市：CN116019419A.
[2]闫天翼,闫子龙,索鼎杰*等. 一种针对脑图谱的皮层靶点精准聚焦方法[P]. 北京市：CN115990316A,2023-04-21.
[3]闫天翼,王雨童,索鼎杰*等. 一种核磁兼容触觉刺激装置[P]. 北京市：CN115956879A.
[4]闫天翼,石忠焱,索鼎杰*等. 一种基于皮层下功能图谱的磁引流调控装置和方法[P]. 北京市：CN115845257A.
[5]闫天翼,江波,索鼎杰*等. 用于触觉刺激的柔性镀膜微针阵列电极、制备方法及应用[P]. 北京市：CN115770343A.
[6]闫天翼,康安顺,索鼎杰*等. 一种面向脑图谱的多层次神经元经颅磁刺激方法[P]. 北京市：CN115721861A.
[7]闫天翼,王恒,索鼎杰*等. 一种位置及方向可调且抗寄生电容的电刺激电极[P]. 北京市：CN113082510A.
所获奖励/荣誉