学科 : 生物医学工程
方向 :智能医学影像、脑机接口、神经调控、视触感知解码
电子邮件 :zhangjian2023@bit.edu.cn
办公地址 :北京理工大学良乡校区生态楼B座309室
个人简历
本人一直致力于研究大脑皮质分层成像与无创脑机接口调控技术,开展了“脑功能设备—脑成像方法—脑调控应用”的全链条研究。相关研究发表在医学影像、康复工程、脑机接口、医学信息工程等领域的知名期刊上,其中以第一作者或通讯作者身份在Molecular Psychiatry、IEEE Internet of Things Journal、IEEE Transactions on Intelligent Transportation Systems、NeuroImage、Psychiatry Research、Human Brain Mapping等期刊上发表SCI论文25篇,出版专著专章1章。相关技术授权国家发明专利12项、国际专利1项、转化1项。部分技术转化至北京智精灵科技有限公司,获得认知障碍诊治相关的NMPA认证,并已在首都医科大学宣武医院等二十余家医院开展了临床应用,取得了显著的临床效果。
教育培训经历
200809-201207 华北电力大学 机械学院 学士
201409-202007 北京理工大学 机电学院 博士
202012-202303 北京理工大学 机电学院 博士后
202203-202303 京都大学(日本) 医学院 访问学者
工作经历
201208-201405 中国兵器集团 晋西工业有限公司 技术员
202303-今 北京理工大学 医学科学与工程学院 预聘助理教授/系副主任
学术任职
脑机接口与神经工程系副主任,国防科技工业局脑机智能学科与技术中心副主任,国际复合医工研究所理事,国际应用脑科学委员会委员。
研究领域
脑科学与仪器研发:视觉触觉脑图谱分析,触觉视觉感知探测装置
智能医学影像:皮层分层磁共振成像技术,高级认知活动的神经解码
脑机接口:脑电信号解码,脑控机器人,脑控无人车,脑控机器手
脑机闭环神经调控:双向闭环脑机交互调控技术,帕金森康复等临床应用
讲授课程
《脑功能分析技术》《医疗仪器设计实验II》《工程制图C》《生物医学工程导论》
教材及专著
参与项目
[1] 2027.01至2030.12,基于个体化SCAN网络皮质分层成像技术的帕金森病脑机调控机制研究,国家自然科学基金面上项目,主持,在研
[2] 2024.01至2026.12,基于介观脑功能成像的帕金森病触觉感知智能诊断模型研究,国家自然科学基金青年基金,主持,在研
[3] 2020.08至2023.02,基于机器学习的视触觉前注意功能预测模型研究,中国博士后科学基金委,特别资助(站前),主持,结题
[4] 2022.06至2023.02,基于介观尺度脑功能成像的触觉感知脑机制与帕金森病早期诊断技术研究,中国博士后科学基金委,面上项目(二等),主持,结题
[5] 2020.06至2022.05,基于精准电刺激调控技术的脑功能增强研究,北京市科学技术委员会,新兴领域融合科技创新,参与,结题
SCI Journal paper
Chen, Y., Liu, T., Cao, L.-Z., Wang, L., Funahashi, S., Tang, X., Wu, J., Meng, W., Zhang, J., & Yan, T. (2025). Multilevel white matter degeneration associated cognitive dysfunction in mild cognitive impairment. Molecular Psychiatry, *31*(2), 835–844. https://doi.org/10.1038/s41380-025-03179-7
Liu, S., Liu, M., Ming, Z., Zhang, D., Luo, J., Liu, Z., Chen, Q., Liu, M., Ma, L., Zhang, J., & Yan, T. (2024). “Pilot” to “embodier”: Brain-controlled robotic arm with the E-VEP paradigm in 3D manufacturing scenarios for the IoT. IEEE Internet of Things Journal, *11*(11), 17210–17212. https://doi.org/10.1109/JIOT.2025.3535560
Liu, S., Ming, Z., Liu, M., Zhang, D., Liu, Z., Chen, Q., Ma, L., Luo, J., Suo, D., Zhang, J., & Yan, T. (2024). Remote-oriented brain-controlled unmanned aerial vehicle for IoT. IEEE Internet of Things Journal, *11*(17), 29202–29214. https://doi.org/10.1109/JIOT.2024.3406837
Yan, T., Liu, S., Liu, M., Zhang, D., Ming, Z., Ma, L., Luo, J., Liu, Z., Chen, Q., Liu, T., Song, Y., Suo, D., & Zhang, J. (2025). A novel nonlinear smooth controller for a brain-controlled driving system in complex driving scenarios. IEEE Transactions on Intelligent Transportation Systems, *26*(7), 9432–9444. https://doi.org/10.1109/TITS.2025.3569256
Wang, Y., Luo, D., Ma, L., Wang, L., Wu, J., Zhang, J., & Yan, T. (2025). Development of a multichannel hand-adaptive tactile stimulation device for somatotopic map of human hand in somatosensory cortex with fMRI. NeuroImage, *310*, 121126. https://doi.org/10.1016/j.neuroimage.2025.121126
Yan, T., Ming, Z., Huang, Y., Liu, Z., Chen, Q., Zhang, D., Liu, M., Suo, D., Zhang, J., & Liu, S. (2025). Enhanced brain-controlled mobile robot based on SE-VEP paradigm with single stimulus. IEEE Transactions on Neural Systems and Rehabilitation Engineering, *33*, 2498–2507. https://doi.org/10.1109/TNSRE.2025.3579373
Wei, X., Zhang, J., Zhang, J., Li, Z., Li, Q., Wu, J., Yang, J., & Zhang, Z. (2025). Investigating the human brain’s integration of internal and external reference frames: The role of the alpha and beta bands in a modified temporal order judgment task. Human Brain Mapping, *46*(5), e70196. https://doi.org/10.1002/hbm.70196
Zhang, J., Yang, Y., Liu, T., Shi, Z., Pei, G., Wang, L., Wu, J., Funahashi, S., Suo, D., Wang, C., & Yan, T. (2023). Functional connectivity in people at clinical and familial high risk for schizophrenia. Psychiatry Research, *328*, 115464. https://doi.org/10.1016/j.psychres.2023.115464
Zhang, J., Ouyang, J., Liu, T., Wang, X., Gao, B., Zhang, J., Luo, M., Kang, A., Yan, Z., Wang, L., Pei, G., Funahashi, S., Wu, J., Zhang, J., & Yan, T. (2025). Triangular wave tACS improves working memory performance by enhancing brain activity in the early stage of encoding. Neuroscience Bulletin, *41*(7), 1213–1228. https://doi.org/10.1007/s12264-025-01413-4
Zhang, J., Yan, Z., Kang, A., Ouyang, J., Ma, L., Wang, X., Wu, J., Suo, D., Funahashi, S., Meng, W., Wang, L., & Zhang, J. (2025). Amplitude of intracranial induced electric fields does not linearly decrease with age: A computational study of anatomical effects in adults. Biosensors, *15*(3), 185. https://doi.org/10.3390/bios15030185
Gao, B., Zhang, J., Zhang, J., Pei, G., Liu, T., Wang, L., Funahashi, S., Wu, J., Zhang, Z., & Zhang, J. (2025). Gamma transcranial alternating current stimulation enhances working memory ability in healthy people: An EEG microstate study. Brain Sciences, *15*(4), 381. https://doi.org/10.3390/brainsci15040381
Zhang, J., Zou, W., Gao, B., Wu, J., Zhang, Z., Zhang, J., Wang, L., & Yan, T. (2025). Regulation of somatosensory temporal discrimination threshold through motor training: An EEG and kinematics study. CNS Neuroscience & Therapeutics, *31*, e70564. https://doi.org/10.1111/cns.70564
EI Journal paper
Pan, H., Zhang, Y., Lang, Y., Suo, D., Zhang, C., & Zhang, J. (2024). Comparing wired and wireless optogenetic control systems: Impact on behavior and efficiency. In EAI WiSATS 2024.
Wang, X., Ouyang, J., Kang, A., Wang, L., Zhang, J., Yan, T., Zhang, J., & Yan, Z. (2023). Gamma tACS reshapes low-dimensional trajectories of brain activity in working memory. In 17th International Conference on Complex Medical Engineering (CME 2023).
zhangjian, et al. (2025). Behavioral performance and neural activation differences between single- and dual-task conditions: An event-related fMRI study. In 2025 19th International Conference on Complex Medical Engineering.
zhangjian, et al.. (2025). Co-activation patterns reveal aberrant brain network dynamics across different stages of Alzheimer’s disease. In 2025 19th International Conference on Complex Medical Engineering.
中文论文
马丽华, 方伯言, 吴景龙, & 张健. (2025). 帕金森病患者触觉脑区的功能与结构梯度. 北京理工大学学报.
专利
所获奖励/荣誉
北京理工大学研究生教育教学成果一等奖 2025 (排名2)
北京理工大学校级优秀个人 (2025)