学科 : 生物医学工程
方向 :生物医学检测和成像，生物医学光谱学技术的临床应用
电子邮件 :ryzh@bit.edu.cn
办公地址 :北京市海淀区中关村南大街5号院北京理工大学7号楼402#
个人简历
北京理工大学预聘助理教授，特别副研究员，硕士生导师；毕业于新加坡国立大学，师从新加坡工程院院士，美国工程院外籍院士Liu Bin教授，主要研究方向：（1）肿瘤标志物的可视化检测和成像技术的开发，（2）面向临床诊断的光谱学技术应用，至今以第一或者通讯作者在Coordin. Chem. Rev., Chem. Sci.，Anal. Chem.， Opt. Lett. 等期刊发表高水平论文30篇，主持国家自然科学基金一项，博士后基金面上项目一项，技术研发课题两项等。研究兴趣：多肽功能探针的开发，巨噬细胞在疾病诊断治疗中的应用。欢迎有责任心、自律、积极向上的同学报考！
教育培训经历
2012.7-2017.2 新加坡国立大学 工学博士 导师：Prof. LIU Bin
2009.9-2012.6 大连理工大学 理学硕士
工作经历
2018．11-2021.5 青岛大学 副教授，特聘教授
2021.7-今 北京理工大学 医学技术学院 预聘助理教授/特别副研究员
学术任职
研究领域
1. 荧光多肽探针的开发及其在肿瘤/神经疾病中的诊疗应用
2. 生物医学光谱学用于临床肿瘤诊断
讲授课程
《分子诊断学》《免疫学》等
教材及专著
参与项目
中国博士后科学基金面上资助，主持，8万元
国家自然科学基金青年项目，主持，25万元
SCI Journal paper
部分代表作 （Selected Publications）：
1. Xiaotong Chen, Yajing Jiang, Jiaxin Liu, Yu Tian, Yifan Deng, Xiaoqiong Li*, Wenbo Wu*, R. Zhang*, et al, Suppressing ROS Production of AIE Nanoprobes by Simple Matrices Optimization for CNS Cell Observation and Minimized Influence of Cytoskeleton Morphology, Chem. Biomed. Imaging, 2024, 2, 775.
2. Qiuyan Li, Ruiqi Ming, Lili Huang*, and Ruoyu Zhang*, Versatile Peptide-Based Nanosystems for Photodynamic Therapy, Pharmaceutics, 2024, 16, 218.
3. Ruoyu Zhang*, Xiaotong Chen, Yuanyuan Cheng, Zixuan Chen, Xiaoqiong Li, and Yulin Deng*, Recent advances of nanomaterials for intervention in Parkinson’s disease in the context of anti-inflammation, Coord. Chem. Rev., 2024, 502, 215616.
4. Ruoyu Zhang*, Yukun Duan, and Bin Liu*; Recent advances of AIE dots in NIR imaging and phototherapy, Nanoscale.,2019,11, 19241-19250.
5. Ruoyu Zhang#, Simon H. P. Sung#, Guangxue Feng, Chong-Jing Zhang, Kenry, Ben Zhong Tang*, and Bin Liu*; AIE probe for specific turn-on quantification of sTfR: an important disease marker for iron deficiency anemia and kidney diseases, Anal. Chem., 2018, 90, 1154–1160.
6. Ruoyu Zhang, Guangxue Feng, Chong-Jing Zhang, Xiaolei Cai, Xiamin Cheng, and Bin Liu*; Real-Time Specific Light-Up Sensing of Transferrin Receptor: Image-Guided Photodynamic Ablation of Cancer Cells through Controlled Cytomembrane Disintegration, Anal. Chem., 2016, 88, 4841–4848.
7. Ruoyu Zhang, Chongjing Zhang, Guangxue Feng, Fang Hu, Jigang Wang and Bin. Liu*; Specific Light-Up Probe with Aggregation-Induced Emission for Facile Detection of Chymase; Anal. Chem., 2016, 88, 9111–9117.
8. Youyong Yuan#, Ruoyu Zhang#, Xiamin Cheng#, Shidang Xu and Bin Liu*; A FRET probe with AIEgen as the energy quencher: dual signal turn-on for self-validated caspase detection, Chem. Sci., 2016, 7, 4245-4250.
9. Ruoyu Zhang#, Youyong Yuan, Jing Liang, Ryan T. K. Kwok, Qing Zhu, Guangxue Feng, Junlong Geng, Ben Zhong Tang, and Bin Liu*; Fluorogen−Peptide Conjugates with Tunable Aggregation-Induced Emission Characteristics for Bioprobe Design, ACS Appl. Mater. Interfaces, 2014, 6 (16), 14302–14310.
10. Ruoyu Zhang, Meng Gao, Shiqiang Bai and Bin Liu*; A fluorescent light-up platform with “AIE + ESIPT” characteristics for multi-target detection both in solution and on paper strip; J. Mater. Chem. B, 2015, 3, 1590-1596.
11. Ruoyu Zhang, Chong-Jing Zhang, Zhegang Song, Jing Liang, Ryan T. K. Kwok, Ben Zhong Tang, and Bin Liu*; AIEgens for real-time naked-eye sensing of hydrazine in solution and on a paper substrate: structure-dependent signal output and selectivity. J. Mater. Chem. C, 2016, 4, 2834-2842.
EI Journal paper
中文论文
专利
所获奖励/荣誉