脑功能磁共振影像动态分析、脑图谱绘制、大脑老化机制探索、阿尔茨海默病和帕金森病诊疗模型构建

《生物医学工程导论》

1.国家自然科学基金委员会, 青年科学基金项目（C类）[原青年科学基金项目], 62406025, 面向帕金森病分型的脑功能信息双向编码和时空间共变模型研究, 2025-01-01 至 2027-12-31, 30万元, 在研, 主持

2.中国博士后科学基金会, 第75批面上资助, 2024M754099, 基于认知映射编码的共波动模式算法研究及脑功能调控应用, 2024-04 至 2025-06, 8万元, 结题, 主持

3.中国博士后科学基金会, 第5批特别资助（站前）, 2023TQ0027, 基于多模态自编码模型的睡眠状态监测及失眠调控应用研究, 2023-07 至 2025-06, 18万元, 结题, 主持

1.Tiantian Liu; Li Wang; Dingjie Suo; Jian Zhang; Kexin Wang; Jue Wang; Duanduan Chen; Tianyi Yan*; Resting-state functional MRI of healthy adults: temporal dynamic brain coactivation patterns, Radiology, 2022, 304(3): 624-632.

2.Tiantian Liu#; Mingjun Wang#; Jian Zhang; Chuyang Ye; Shintaro Funahashi; Jianghong Liu*; Li Wang*; Tianyi Yan*; the Alzheimer's Disease Neuroimaging Initiative; Brain network dynamics in patients with single- and multiple-domain amnestic mild cognitive impairment, Alzheimers Dementia, 2024, doi: 10.1002/alz.14227.

3.Yu Chen, Tiantian Liu*, Li-Zhi Cao, Li Wang, Shintaro Funahashi, Xiaoying Tang, Jinglong Wu, Wei Meng, Jian Zhang*, Tianyi Yan*; Alzheimer’s Disease Neuroimaging Initiative; Multilevel white matter degeneration associated cognitive dysfunction in mild cognitive impairment. Molecular Psychiatry, 2025, doi: 10.1038/s41380-025-03179-7.

4.Mengmeng Wu; Tiantian Liu*; Xin Dai; Chuyang Ye; Jinglong Wu; Shintaro Funahashi; Tianyi Yan*. (2024). HMDA: A Hybrid Model with Multi-scale Deformable Attention for Medical Image Segmentation. IEEE journal of biomedical and health informatics, PP. doi:10.1109/jbhi.2024.3469230.

5.Bin Wang#; Xi Zhang#; Tingting Pan; Ting Li; Tiantian Liu*; Tianyi Yan*; Large-Scale Brain Mediation Network based on Resting-State functional MRI. Communications Biology, 2025. Accept.

6.Gongshu Wang; Ning Jiang; Yunxiao Ma; Dingjie Suo; Tiantian Liu*; Shintaro Funahashi; Tianyi Yan*; Using a deep generation network reveals neuroanatomical specificity in hemispheres, Patterns, 2024, doi: 10.1016/j.patter.2024.100930.

7.Lisong Yin#; Chuyang Ye#; Tiantian Liu*; Jinglong Wu; Tianyi Yan*; UniCross: Balanced Multimodal Learning for Alzheimer’s Disease Diagnosis by Uni-modal Separation and Metadata-guided Cross-modal Interaction, In: International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI). pp. 638–648. Springer (2025)

8.Tiantian Liu#; Zhongyan Shi#; Jian Zhang; Kexin Wang; Yuanhao Li; Guangying Pei; Li Wang; Jinglong Wu; Tianyi Yan*; Individual functional parcellation revealed compensation of dynamic limbic network organization in healthy ageing, Human Brain Mapping, 2022, 44(2): 744-761.

9.Ting Li; Tiantian Liu*; Jian Zhang; Yunxiao Ma; Gongshu Wang; Dingjie Suo; Bowen Yang; Xiu Wang; Shintaro Funahashi; Kai Zhang; Boyan Fang; Tianyi Yan*; Neurovascular coupling dysfunction of visual network organization in Parkinson's disease, Neurobiology of Disease, 2023, 188: 106323.

10.Tiantian Liu; Yan Yan; Jing Ai; Duanduan Chen; Jinglong Wu; Boyan Fang*; Tianyi Yan*; Disrupted rich-club organization of brain structural networks in Parkinson’s disease, Brain Structure and Function, 2021, 226(7): 2205-2217.

11.Yunxiao Ma, Li Wang*, Ting Li, Jian Zhang, Shintaro Funahashi, Jinglong Wu, Xiu Wang, Kai Zhang, Tiantian Liu*, Tianyi Yan. Disrupted coordination between primary and high-order cognitive networks in Parkinson's disease based on morphological and functional analysis. Brain Structure and Function. 2025 Apr 10;230(3):48. doi: 10.1007/s00429-025-02909-5. PMID: 40208328.

12.Ziteng Han#; Tiantian Liu#; Zhongyan Shi; Jian Zhang; Dingjie Suo; Li Wang; Duanduan Chen; Jinglong Wu; Tianyi Yan*; Investigating the heterogeneity within the somatosensory-motor network and its relationship with the attention and default systems, PNAS Nexus, 2023, 2(9): pgad276.

13.Yunyan Xie#; Tiantian Liu#; Jing Ai; Duanduan Chen; Yiran Zhuo; Guanglei Zhao; Shuai He; Jinglong Wu; Ying Han*; Tianyi Yan*; Changes in centrality frequency of the default mode network in individuals with subjective cognitive decline, Frontiers in Aging Neuroscience, 2019, 11: 118.

14.Tiantian Liu#; Jian Zhang#; Xiaonan Dong; Zhucheng Li; Xiaorui Shi; Yizhou Tong; Ruobing Yang; Jinglong Wu; Changming Wang*; Tianyi Yan*; Occipital alpha connectivity during resting-state electroencephalography in patients with ultra-high risk for psychosis and schizophrenia, Frontiers in Psychiatry. 2019;10:9. doi: 10.3389/fpsyt.2019.00553.

15.Tiantian Liu; Zilong Yan; Ziteng Han; Jian Zhang; Boyan Fang; Tianyi Yan; Cortico–subcortical spatiotemporal dynamics in Parkinson’s disease can be modulated by transcranial alternating current stimulation, Brain Science Advances, 2023;9(2):114-135. doi:10.26599/BSA.2023.9050009.

1.刘田田; 闫天翼; 吴蒙蒙; 叶初阳; 代欣; 雷泽浩; 一种基于随机超分学习辅助和多层特征映射的腹部器官分割方法及系统, 2025-9-16, 中国, ZL202411968366.8 (专利)

2.刘田田; 闫天翼; 张健; 王可欣; 王丽; 闫子龙; 一种基于动态梯度的个体化大脑状态检测方法及系统, 2024-05-23, 中国, CN202410647701.8 (专利)

3.刘田田; 闫天翼; 闫子龙; 张健; 康安顺; 一种靶向大脑主从功能状态的个体化刺激控制系统及方法, 2024-11-01, 中国, ZL202311750640.X (专利)

第十八届国际复合医工学会会议（CME2024）最佳摘要奖

2023年北京市优秀毕业生